Nitric Oxide with Dr. Nathan Bryan

virus Prevention, testing, production and supplementation
Nathan S. Bryan, PhD.

Nathan S. Bryan, PhD.

International leader in molecular medicine and nitric oxide biochemistry

Dr. Bryan is an international leader in molecular medicine and nitric oxide biochemistry.

Specifically, Dr. Bryan was the first to describe nitrite and nitrate as indispensable nutrients required for optimal cardiovascular health. He was the first to demonstrate and discover an endocrine function of nitric oxide via the formation of S-nitrosoglutathione and inorganic nitrite.

Dr. Bryan has been involved in nitric oxide research for the past 18 years and has made many seminal discoveries in the field. These discoveries and findings have transformed the development of safe and effective functional bioactive natural products in the treatment and prevention of human disease and may provide the basis for new preventive or therapeutic

Dr. Bryan has published a number of highly cited papers and authored or edited 5 books.

Nitric Oxide is a very important signaling molecule that is naturally produced in our body but the problem is that there are lifestyle factors that hinder the production of NO. Therefore, it has been linked to cardio-vascular health, sexual and mental health as well as popular as a sports supplement (you’ve probably heard about beetroot extract). But can it be also a good supplement to prevent virus infections? Dr. Bryan believes it can.

You can find the previous episode with Dr. Bryan below.

Time Stamps

00:02:00 Role of Nitric Oxide in immune function and Corona virus prevention. Without nitric oxide you cannot mobilize immune cells.
00:05:00 How Nitric Oxide inhibits replication of Corona virus as proven on mice models. We don’t know if it translates to humans as well.
00:07:50 The role of NO in health and wellness
00:09:30 Humans are fear-based reactive beings
00:11:45 How beneficial is NO supplementation and what is the best way to restore your NO production (STOP chronic use of antibiotics, NSAID drugs, mouth wash, START eating green leafy vegetables, being active)
00:16:00 How NO supplements work and why they are a waste of money most of the time. You need to have good food, good oral health and bacteria.
00:19:00 How to test your NO status
00:24:30 How to figure out if you are NO deficient
  • Symptom of deficiency: increase in BP and vascular dysfunction (erectile dysfunction)

00:26:50 What is the future of nitric oxide research? We are just starting to understand it.
00:30:30 How to choose a working nitric oxide supplement and not waste your money
beetroot =/= nitrate and nitrate =/= nitric oxide

How to choose a working nitric oxide supplement:

  • look for patents
  • able to show improvements in patients in clinical trials
00:33:54 Nitric oxide in athletes
00:38:00 How did nitric oxide research influence Dr. Bryan’s lifestyle
00:40:00 One advice Dr. Bryan would give everyone
You get sick for two reasons only: You are exposed to something your body does not need and you are not getting enough of what your body needs.


The devices for testing endothelial function or nitric oxide production are EndoPat and MaxPulse. Those are the most commonly used devices and give really good information